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The corrections required to do this operation will be encapsulated in the USPLINE file, otherwise used primarily for spatial corrections. If you attempt to run "applycor" using a USPLINE file that has not had sensitivity correction values added to it by "qecor" or "analmr", "applycor" will notice that the USPLINE is unhelpful and will exit without changing anything.
On the grounds that any correction made to an intensity measurement has a finite error associated with it, the variances associated with each modified intensity measurement will be inflated according to the following formula:
The final standard deviation will the square root of var'. Here M is the magnitude of the correction applied to I, i.e.
<M> is the mean value of the corrections, and Q is an inflation factor. By default, Q is 0.1, but it may be set to something else at run time. If we set Q to zero, then the standard deviations will simply be rescaled, rather than inflated. Research to date suggests that setting Q to zero gives the lowest R(merge) values, but that result is far from definitive, and it may depend on the quality of the remapping.